Systems and methods for controlling at least one security device based on the behavior of at least one tag. The methods comprise: generating sensor data relating to movement by at least one sensor disposed in a first tag; analyzing the sensor data to determine if an item to which the first tag is coupled is being handled in an unusual, abnormal or nervous manner; determining if an enterprise system has lost communicative contact with the first tag coupled to the item that is being handled in an unusual, abnormal or nervous manner; and causing an operational state of the security device to change in response to the loss of the communicative contact between the enterprise system and the first tag.