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L-menthol dosage forms having a proteinaceous coating for enhanced storage stability

Invented by: Syed M. Shah
Boca Raton, FL

Fred Hassan
Boca Raton, FL Applicant: Name City State Country Type Zx Pharma, LLC Boca Raton FL US

Originally Assigned to: Zx Pharma, LLC
Boca Raton, FL Family ID: 1000004294262
[Now assigned to . . .]

Issued:2019-09-24
Filed:2015-10-06
Application No:14876465
Examined by:Arnold; Ernst V

A storage stable L-menthol composition including a tablet, caplet, capsule, or sachet dosage form has therein a core containing crystalline L-menthol and at least one pharmaceutical excipient. A proteinaceous coating of a continuous film of proteinaceous material is over the core. The film is effective to substantially prevent the crystalline L-menthol from volatilizing and leaving the core when stored at a temperature of 40 degrees C. and 75% relative humidity from between 1 day to 30 days. The dosage form contains an effective amount of the crystalline L-menthol for treating a gastrointestinal disorder.

[pdf] U.S. Pat. No. 10,420,730

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