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Tetracyclic compounds as c-Met inhibitors

Invented by: Tomas Vojkovsky
San Francisco, CA

Marcel Koenig
Boca Raton, FL

Fang-Jie Zhang
Sunnyvale, CA

Jingrong Cui
San Diego, CA

Originally Assigned to: Sugen, Inc.
San Diego, CA
[Now assigned to . . .]

Issued:2006-05-02
Filed:2004-06-29
Application No:10878632
Examined by:Balasubramanian; Venkataraman

The present invention relates to compounds of the Formulae (I) and (II), wherein R.sub.1-R.sub.10 and G are defined herein, and their pharmaceutically acceptable salts. These compounds modulate the activity of c-Met and are therefore expected to be useful in the prevention and treatment of c-Met related disorders such as cancer. ##STR00001##

[pdf] U.S. Pat. No. 7,037,909

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