A combined active sealing system for connecting a panel to a frame of a door/window comprises a plurality of active sealing systems, a seal activation system, and an electronic control system. Each of the plurality of active sealing systems includes an anchor for engaging one of the panel and the frame, and an actuator connected to the anchor and for driving the anchor. In a closed position of the panel relative to the frame, the anchor is movable between a locked position and an unlocked position. The seal activation system is connected to at least one of the actuators of the plurality of active sealing systems. The electronic control system controls the seal activation system.